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Electronic cigarettes ‘could damage your lungs’ as they cause less oxygen to be absorbed by the blood

Around 650,000 smokers are thought to be using the inhalers to help them kick the habit

By Daniel Miller

PUBLISHED: 04:53 GMT, 3 September 2012 | UPDATED: 11:51 GMT, 3 September 2012

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They are touted as a safe alternative to smoking, but electronic cigarettes could damage the lungs, latest research has found.

The devices were found to cause an immediate rise in airway resistance in the lungs - meaning less oxygen is absorbed by the blood.

On average the effect lasted for ten minutes, a report presented at the European Respiratory Society’s Annual Congress in Vienna found.
Concerns: E-cigarettes were found to cause an immediate rise in airway resistance in the lungs - meaning less oxygen was being absorbed by the blood

Concerns: E-cigarettes were found to cause an immediate rise in airway resistance in the lungs - meaning less oxygen was being absorbed by the blood

Electronic cigarettes deliver nicotine through a vapour rather than smoke and there has been much debate over their safety.

Around 650,000 smokers are thought to be using the inhalers - which look like cigarettes or pens - to help them kick the habit.

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But at present the devices - which are all imported from China - do not have to undergo any safety checks before being put on sale in high street chemists.

To investigate, researchers from the University of Athens examined the effects on eight people who had never smoked and 24 smokers, 11 with normal lung function and 13 people with either chronic obstructive pulmonary disease (COPD) or asthma.

Each person used an electronic cigarette for 10 minutes. The researchers then measured their airway resistance using a number of tests.

For all of those involved the e-cigarette caused an immediate rise in airway resistance, lasting for ten minutes.

It was more pronounced in smokers than non smokers, although not immediately noticeable in those with existing chronic breathing difficulties.

Professor Christina Gratziou, Chair of the ERS Tobacco Control Committee, said: 'We do not yet know whether unapproved nicotine delivery products, such as e-cigarettes, are safer than normal cigarettes, despite marketing claims that they are less harmful.

'This research helps us to understand how these products could be potentially harmful.
Around 650,000 smokers are thought to be using the inhalers - which look like cigarettes or pens - to help them kick the habit

Around 650,000 smokers are thought to be using the inhalers - which look like cigarettes or pens - to help them kick the habit

'We found an immediate rise in airway resistance in our group of participants, which suggests e-cigarettes can cause immediate harm after smoking the device.

'More research is needed to understand whether this harm also has lasting effects in the long-term.

‘The ERS recommends following effective smoking cessation treatment guidelines based on clinical evidence which do not advocate the use of such products.’

Ministers are concerned that some brands of E-cigarettes may contain very high levels of nicotine - the addictive substance in cigarettes has also been linked to cancer.

Figures from the charity Action on Smoking and Health show that 2 million Britons have tried e-cigs at least once, with 650,000 currently using them.

Deborah Arnott, spokesman for the charity said: We certainly wouldnt want smokers to think its better to go back to using cigarettes rather than e-cigarettes.

Wed want to see them properly regulated. Presently they are made in China but there are not properly regulated on how much nicotine they contain or on their safety quality.

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New clinical trials proves electronic cigarettes are significantly more effective than government approved smoking cessation devices
PRWeb Fri, Jul 13, 2012
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Recent clinical trials outlined within Effectiveness of web-based tailored smoking cessation advice reports (iQuit): a randomised trial. By Mason D, Gilbert H, Sutton S, Addiction 2012 and Dhelaria RK, Friderici J, Wu K, Gupta E, Khan C, Rothberg MB. Effectiveness of varenicline for smoking cessation at 2 urban academic health centers. European Journal of Internal Medicine 2012; 23(5):461-4. identified that government approved smoking cessation devices such as nicotine replacement therapies such as patches and gum and web based therapies have a quit success rate of less than 10%, where as other studies prove electronic cigarettes have seen 50% of subjects either quit completely or cut down considerably.
So why does the FDA not approve electronic cigarettes as a smoking cessation device?

(PRWEB UK) 13 July 2012
Can electronic cigarettes help smokers quit and if they can, why has the FDA not approved them as a smoking cessation device?
An electronic cigarette, or e cigarette is an electrical device that simulates the act of cigarette smoking by producing an inhaled vapor bearing the characteristics of tobacco smoke, but without the nicotine content. Despite the fact that they have been available since 2003, and there have been lots of studies indicating that e cigarette are far more effective as an anti-smoking device (also known as a smoking cessation device), than current measures, the government still refuse to approve them as a smoking cessation device and http://www.the-best-electronic-cigarette.com/index.php investigates into this further.
There are several online resources documenting the argument for making e cigarettes a smoking cessation device and most of these can be traced back to Dr Michael Siegel, a huge supporter of tobacco control.
Who is Dr Michael Siegel?
Dr Michael Siegel is a professor with 21 years of experience in tobacco control. He founded the Centre for Public Accountability in Tobacco Control in the US and is dedicated to ensuring the ethical and honest practice of tobacco control by anti-smoking organizations. He has produced numerous scientific papers, interviews and blogs criticizing the current anti-smoking methods and staunchly champions e cigarettes as effective smoking cessation devices.

His views are controversial in the eyes of the law as he exposes the financial motives of the government for not legalising e cigarettes, in favour of allowing the current tobacco consumption to continue.
Current anti-smoking campaigns Vs electronic cigarettes
Current anti-smoking devices include nicotine patches and web-based therapy. However, according to scientific papers, both of these methods are almost useless.

The study, Effectiveness of web-based tailored smoking cessation advice reports (iQuit): a randomised trial. By Mason D, Gilbert H, Sutton S, Addiction 2012 identified:
Web-based therapy had the following success rate:

The tailored advice group had a six-month cessation rate of 9.3%
The non-tailored advice group had a cessation rate of 9.3%.
The study, Dhelaria RK, Friderici J, Wu K, Gupta E, Khan C, Rothberg MB. Effectiveness of varenicline for smoking cessation at 2 urban academic health centers. European Journal of Internal Medicine 2012; 23(5):461-4 identified;
Nicotine replacement has the following success rate:

Long term quit rate 8%
Therefore both government-approved smoking cessation methods have a success rate for quitting smoking of less than 10%.
The electronic cigarette contains a nicotine/propylene glycol solution and vaporizes the nicotine. There is no tobacco, no tar and it does not contain any of the thousands of other constituents of tobacco smoke. The amount of nicotine delivered can also be controlled by the user. Therefore according to Dr Michael Siegel, although he cannot exactly say how safe e cigarettes are:

I can say is that it is substantially safer than the conventional cigarette. Inhaling nicotine cannot be nearly as dangerous as inhaling nicotine plus thousands of other chemicals.

Dr Michael Siegel’s blog tobaccoanalysis.blogspot identifies many studies which highlight e cigarettes as an effective smoking cessation device. They include:
The Polosa study, a clinical trial of electronic cigarettes among smokers with no motivation to quit, in which more than 50% of the subjects either quit or cut down substantially (by more than half) on the amount they smoked.
The results of numerous surveys and focus groups as well as the abundant anecdotal evidence of the many thousands of people who have successfully quit or greatly reduced their cigarette consumption with the help of electronic cigarettes.
So why will the government not approve e-cigs as a smoking cessation device?
Dr Michael Siegel gives clear evidence on http://www.e-cigarette-forum.com for the reasons that the government wont approve electronic cigarettes. In an article he wrote in response to a possible ban, he notes the relationship between the government and the manufacturers of current smoking cessation devices:

The only real threat that electronic cigarettes pose is not to the public’s health, but to the profits of the pharmaceutical companies, which manufacture competing products (nicotine replacement therapy). If lots of smokers turn to electronic cigarettes, rather than pharmaceuticals, in order to try to quit smoking, then the pharmaceutical companies stand to lose lots of money.

He then identifies that in 2008 Frank Lautenberg, a US Senator from New Jersey, who wants the US Food and Drug Administration to ban electronic cigarettes due to his concerns about safety, received $128,000 towards his election campaign in donations from pharmaceutical companies. Therefore if pharmaceutical sales were hit with a rival smoking cessation product (electronic cigarettes), the money that pharmaceutical companies pass to the government would be significantly reduced.
Dr Michael Siegel acknowledges this by saying:

So perhaps it is not surprising that Senator Lautenberg, (US Senator) is standing up to protect the financial interests of the pharmaceutical companies over the interests of the public’s health.
So, can electronic cigarettes help smokers quit? The facts are;
1.Inhaling nicotine only is better than inhaling nicotine plus all of the other toxic substances found in cigarettes (tar etc.).

2.Clinical trials, studies and focus groups have all identified that e cigarettes are an extremely effective smoking cessation device and clinical trials involving subjects who had no motivation to quit, did quit and others significantly reducing their smoking intake.

3.Dr Micheal Siegel a passionate and knowledgeable professor who has dedicated 21 years of his life to tobacco control, furiously advocates for the government to make e cigarettes a marketable smoking cessation device due to the health benefits over traditional cigarettes and due to them being significantly more effective for quitting smoking than the current government approved methods.
Given all this evidence, http://www.the-best-electronic-cigarette.com/index.php feel it is safe to say that ‘yes’ electronic cigarettes can help smokers quit, however the US governments refuse to concede this.
Robert Patrick
info@the-best-electronic-cigarette.co.uk
07967 920583
Email Information

So perhaps it is not surprising that Senator Lautenberg, (US Senator) is standing up to protect the financial interests of the pharmaceutical companies over the interests of the public’s health.
So, can electronic cigarettes help smokers quit? The facts are;
1.Inhaling nicotine only is better than inhaling nicotine plus all of the other toxic substances found in cigarettes (tar etc.).

2.Clinical trials, studies and focus groups have all identified that e cigarettes are an extremely effective smoking cessation device and clinical trials involving subjects who had no motivation to quit, did quit and others significantly reducing their smoking intake.

3.Dr Micheal Siegel a passionate and knowledgeable professor who has dedicated 21 years of his life to tobacco control, furiously advocates for the government to make e cigarettes a marketable smoking cessation device due to the health benefits over traditional cigarettes and due to them being significantly more effective for quitting smoking than the current government approved methods.
Given all this evidence, http://www.the-best-electronic-cigarette.com/index.php feel it is safe to say that ‘yes’ electronic cigarettes can help smokers quit, however the US governments refuse to concede this.

The only real threat that electronic cigarettes pose is not to the public’s health, but to the profits of the pharmaceutical companies, which manufacture competing products (nicotine replacement therapy). If lots of smokers turn to electronic cigarettes, rather than pharmaceuticals, in order to try to quit smoking, then the pharmaceutical companies stand to lose lots of money.

by da way…i only sell USA made e-liquid…not china…thx

Boston University School of Public Health study
A study by researchers at the Boston University School of Public Health in 2010 concluded that electronic cigarettes were safer than real cigarettes and may aid in breaking the habit of smoking. Researchers said that while further studies on electronic cigarettes were needed, “few, if any, chemicals at levels detected in electronic cigarettes raise serious health concerns.” Electronic cigarettes were found to be “much safer” than traditional tobacco ones, and had a level of toxicity similar to existing nicotine replacements.[32][33][34]
In the report, the level of carcinogens in electronic cigarettes was found to be up to 1,000 times lower than regular cigarettes. It also said early evidence shows that electronic cigarettes may help people to stop smoking by simulating a tobacco cigarette.[

An important thing to remember when making the transition from tobacco cigarettes to the e-cigarette is that there are many side effects from quitting tobacco products that may be mis-interpreted as e-cigarette side effects.

The fact that smoking is injurious to health has been around for several decades. Nothing is enlightening about that fact, nor does it sound like a warning anymore. As a smoker, it is difficult to quit the addiction over night. It can take months to years to finally become a non-smoker. While it makes no sense why cigarette manufacturers exist when they sell their products with warnings of injury, they still continue to make millions. Fortunately, you don’t have to remain slave to the cigarette companies.

Good News for Smokers

E-cigarettes are an innovative invention designed particularly for smokers of all levels. If you are looking to give up the habit but your body doesn’t allow you to, e-cigarettes can prove extremely beneficial. Quite simply, an e-cig is an electronic device that works like a cigarette, without the hazards. It contains zero tobacco and does not use flame to give off harmful carbon monoxide. The device contains pleasant E liquid - a blend of fluid nicotine, glycogen and water. The inbuilt atomizer heats up the liquid, giving off nicotine minus the harmful vapour.

The e-cigarette resembles the conventional tobacco cigs; it even gives off what appears to be smoke, but in reality it is water vapour with other harmless substances. These devices are safe not only to smokers but even to others present nearby.

Pleasant E Liquid Flavours

The E liquid comes in a wide variety of enjoyable flavours. The liquid contains different levels of nicotine content to suit your taste. If you enjoy pure nicotine, you can purchase liquid that emphasis the nicotine flavour. However, you can choose from exotic flavours such as cherry, orange, coconut, floral, or your traditional flavours such as tobacco, cinnamon, menthol, liquorish, and so on. Most online e-cig stores offer DIY starter kits to add nicotine levels and flavour of your choice. Evidently, smoking is no longer just smoking.

Buy from Trusted Source

When purchasing liquid for your electronic cigarette, ensure that the supplier is reputable and licensed. Buying from an uncertified dealer can be detrimental to your heath. Also make sure the manufacture is renowned in the trade. Although this can be costly, it is worth protecting your health. E liquid by a trusted supplier is tested to ensure the right quantity of nicotine and zero impurities.

You can now enjoy new flavours of smoking without injuring your health. The E liquid has become a wide-selling item across the world, with countless smokers no longer endangering their lives or that of others.

Albert Wilson is an independent health awareness consultant who writes contents on pleasant E liquid and have deep knowledge of nicotine e liquid.

Read more: E-Liquid for an Enjoyable and Safe Smoking Experience http://www.sooperarticles.com/health-fi … z29jtEkXlR

E-cigarettes are an innovative invention designed particularly for smokers of all levels. If you are looking to give up the habit but your body doesn’t allow you to, e-cigarettes can prove extremely beneficial. Quite simply, an e-cig is an electronic device that works like a cigarette, without the hazards. It contains zero tobacco and does not use flame to give off harmful carbon monoxide. The device contains pleasant E liquid - a blend of fluid nicotine, glycogen and water. The inbuilt atomizer heats up the liquid, giving off nicotine minus the harmful vapour.

The e-cigarette resembles the conventional tobacco cigs; it even gives off what appears to be smoke, but in reality it is water vapour with other harmless substances. These devices are safe not only to smokers but even to others present nearby.

Electronic cigarettes do not damage the heart
First-hand smoke, second-hand smoke or electronic cigarettes
Topics: Cardiovascular Disease Prevention - Risk Assessment and Management
Date: 25 Aug 2012
Electronic cigarettes have no acute adverse effects on cardiac function, according to research presented today at an ESC Congress 2012 press conference by Dr Konstantinos Farsalinos from Greece.

Abstract

Smoking is the most preventable risk factor for cardiac and lung disease and is expected to cause 1 billion deaths during the 21st century. Electronic cigarettes have been marketed in recent years as a safer habit for smokers, with several millions of people already using them worldwide.

Electronic cigarettes simulate the effect of smoking by producing an inhaled vapor. The device consists of a battery, a cartridge containing liquid and a heating element which gets warm and evaporates the liquid. Laboratory analyses of the liquids show that they are less toxic than regular cigarettes. Most studies have found no nitrosamines, but even in studies where nitrosamines were found, the levels detected were 500-1400 times less than the amount present in one tobacco cigarette. This means that electronic cigarettes must be used daily for 4-12 months to get the amount of nitrosamines present in a single tobacco cigarette.

Since heart disease is the main cause of morbidity and mortality in smokers, with 40% of deaths in smokers due to coronary artery disease alone, the research team decided to perform the first clinical study of the acute effects of electronic cigarettes on cardiac function.
They decided to compare their results with the acute effects of regular cigarettes on cardiac function since electronic cigarettes are marketed to smokers only, as an alternative habit.

Previous studies from the research group and several others have shown that acute smoking inhalation produces significant defects in myocardial function. This indicates that subclinical dysfunction is already present in apparently healthy asymptomatic young people who smoke tobacco cigarettes. The goal was to evaluate whether these signs of preclinical disease appear in a similar population after using electronic cigarettes.

The researchers measured myocardial function in 20 healthy young daily smokers aged 25-45 years before and after smoking one tobacco cigarette and 22 daily electronic cigarette users of similar age before and after using the device for 7 minutes.

Experienced users of electronic cigarettes were studied because they use the device more intensively than first-time users. Although both groups were of equal age, users of electronic cigarettes had a 44% higher lifetime tobacco smoking exposure compared to current smokers.

For the electronic cigarettes, a commercially available liquid with a nicotine concentration of 11mg/ml was used (NOBACCO USA Mix). This was tested by an independent toxicology laboratory and found to contain no nitrosamines or polycyclic aromatic hydrocarbons.

Myocardial function was examined using cardiac ultrasound (echocardiography) and hemodynamic measurements (blood pressure and heart rate).

The researchers found that smoking one tobacco cigarette led to significant acute myocardial dysfunction but electronic cigarettes had no acute adverse effects on cardiac function. Smoking a tobacco cigarette had important hemodynamic consequences, with significant increases in systolic and diastolic blood pressure and in heart rate. In contrast, electronic cigarettes produced only a slight elevation in diastolic blood pressure. Dr Farsalinos said: This is an indication that although nicotine was present in the liquid used (11mg/ml), it is absorbed at a lower rate compared to regular cigarette smoking.

The echocardiography examination focused on the function of the left ventricle, the part of the heart that receives oxygenated blood from the lungs (filling or diastolic phase) and then delivers the blood to the whole body (pumping or systolic phase). The investigators found significant defects in the diastolic phase of left ventricular function after smoking one cigarette, with four echocardiographic parameters indicating worsening function. In contrast, none of the echocardiographic parameters showed any significant worsening in subjects after using the electronic cigarette. Diastolic dysfunction is very important because it is usually the first defect that is detected before any clinically-evident cardiac disease develops, said Dr Farsalinos.

He added: It is too early to say whether the electronic cigarette is a revolution in tobacco harm reduction but the potential is there. It is the only available product that deals with both the chemical (nicotine delivery) and psychological (inhaling and exhaling smoke, holding it, etc) addiction to smoking, laboratory analyses indicate that it is significantly less toxic and our study has shown no significant defects in cardiac function after acute use.

Dr Farsalinos continued: More clinical studies need to be done before suggesting that this is a revolutionary product. However, considering the extreme hazards associated with cigarette smoking, currently available data suggest that electronic cigarettes are far less harmful and substituting tobacco with electronic cigarettes may be beneficial to health.

Dr Farsalinos will also present his results during an ESC Congress 2012 scientific session tomorrow.

Contributors:
Konstantinos Farsalinos, MD1, Dimitris Tsiapras, MD1, Stamatis Kyrzopoulos, MD1, and Vassilis Voudris, MD1
1 Onassis Cardiac Surgery Center, Athens, Greece

Authors: Dr Konstantinos Farsalinos (Greece), Onassis Cardiac Surgery Center

ESC Press Office

For background information, please contact the ESC Press Office.
For independent comment on site, please contact Tanya Kenny, +4917610572544

Notes to editor
About the European Society of Cardiology
The European Society of Cardiology (ESC) represents more than 75,000 cardiology professionals across Europe and the Mediterranean. Its mission is to reduce the burden of cardiovascular disease in Europe.

About ESC Congress 2012
ESC Congress 2012 will take place from 25 to 29 August at the Messe Mnchen centre in Munich, Germany. Information on the scientific programme is available here. More information on ESC Congress 2012 is available from the ESC Press Office or contact us at press@escardio.org

References This press release accompanies both a presentation and an ESC press conference at the ESC Congress 2012. The press release has been written by the investigator and edited by the ESC and does not necessarily reflect the opinion of the European Society of Cardiology.

Refers to session: Tobacco: from early damage to late impact

Refers to press conference: First-hand smoke, second-hand smoke or electronic cigarettes

He added: It is too early to say whether the electronic cigarette is a revolution in tobacco harm reduction but the potential is there. It is the only available product that deals with both the chemical (nicotine delivery) and psychological (inhaling and exhaling smoke, holding it, etc) addiction to smoking, laboratory analyses indicate that it is significantly less toxic and our study has shown no significant defects in cardiac function after acute use.

Dr Farsalinos continued: More clinical studies need to be done before suggesting that this is a revolutionary product. However, considering the extreme hazards associated with cigarette smoking, currently available data suggest that electronic cigarettes are far less harmful and substituting tobacco with electronic cigarettes may be beneficial to health.

Dr Farsalinos will also present his results during an ESC Congress 2012 scientific session

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